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ea0025p3 | Bone | SFEBES2011

Evaluation of the association between serotonin and bone mineral density in patients with neuroendocrine tumours

Gupta Piya Sen , Drake William M , Akker Scott A , Chew Shern L , Grossman Ashley B , Druce Maralyn R

Introduction: Bone mineral density (BMD) and fracture tendency are influenced by diet, activity, drugs, and hormones. Recent studies highlight an inverse relationship between serotonin and BMD, of uncertain mechanism.Purpose: We investigated the relationship between serotonin metabolites and BMD in patients with sporadic neuroendocrine tumours (NETs), with and without the carcinoid syndrome.Materials and methods: One-year prospecti...

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ea0048oc4 | Oral Communications | SFEEU2017

One year efficacy, safety and tolerability outcomes of endoscopic proximal intestinal exclusion therapy using the Endobarrier device: institution of the UK’s first National Health Service Endobarrier service for type 2 diabetes and obesity

Gupta Piya Sen , Yadagiri Mahender , Irwin Susan , Burbridge Wyn , Gandhi Hardeep , Alden Rachel , Bleasdale John , Fogden Ed , Anderson Mark , Ryder Bob

Introduction: Our institution leads a UK, multicentre, randomised controlled trial (REVISE-Diabesity ISRCTN00151053) investigating the interaction of Endobarrier therapy, a 60 cm endoscopically implanted proximal intestinal liner, with glucagon-like peptide-1 drug therapy.Aims: To evaluate whether acquired experience could translate into establishment of an effective and safe NHS Endobarrier service in patients with diabesity.Metho...

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Endocrine Abstracts

Evaluation of the association between serotonin and bone mineral density in patients with neuroendocrine tumours

One year efficacy, safety and tolerability outcomes of endoscopic proximal intestinal exclusion therapy using the Endobarrier device: institution of the UK’s first National Health Service Endobarrier service for type 2 diabetes and obesity

BiosciAbstracts